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2 article(s) from Biavatti, Maique W

Three new trixane glycosides obtained from the leaves of Jungia sellowii Less. using centrifugal partition chromatography

Luíse Azevedo,
Larissa Faqueti,
Marina Kritsanida,
Antonia Efstathiou,
Despina Smirlis,
Gilberto C. Franchi Jr,
Grégory Genta-Jouve,
Sylvie Michel,
Louis P. Sandjo,
Raphaël Grougnet and
Maique W. Biavatti

Beilstein J. Org. Chem. 2016, 12, 674–683, doi:10.3762/bjoc.12.68

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Graphical Abstract

Figure 1: UPLC profile of the butanol fraction of the leaves of Jungia sellowii after shaking the flask with ...

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Figure 2: Structures of compounds 1–3.

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Figure 3: COSY and HMBC correlations of compounds 1–3.

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Figure 4: NOESY correlations of compounds 1–3.

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Figure 5: ECD spectra of compounds 1–3.

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Album

Supp Info

Full Research Paper

Published 12 Apr 2016

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Pyridinoacridine alkaloids of marine origin: NMR and MS spectral data, synthesis, biosynthesis and biological activity

Louis P. Sandjo,
Victor Kuete and
Maique W. Biavatti

Beilstein J. Org. Chem. 2015, 11, 1667–1699, doi:10.3762/bjoc.11.183

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Graphical Abstract

Figure 1: Fragments produced by the FAB–MS of dehydrokuanoniamine B (20) [42].

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Figure 2: Fragments produced by the EIMS of sagitol (26) [55].

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Figure 3: Fragments produced by the EIMS of styelsamine B (4) [45].

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Figure 4: Fragments produced by the EIMS of styelsamine D (6) [45].

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Figure 5: Fragments produced by the EIMS of subarine (37) [40].

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Scheme 1: Synthesis of styelsamine B (4) and cystodytin J (1) [58].

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Scheme 2: Synthesis of sebastianine A (38) and its regioisomer 39 [59].

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Scheme 3: Synthesis route A of neoamphimedine (12) [61].

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Scheme 4: Synthesis route B of neoamphimedine (12) [62].

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Scheme 5: Synthesis of arnoamines A (40) and B (41) [63].

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Scheme 6: Synthesis of ascididemin (42) [65].

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Scheme 7: Synthesis of subarine (37) [66,67].

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Scheme 8: Synthesis of demethyldeoxyamphimedine (9) [68].

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Scheme 9: Synthesis of pyridoacridine analogues related to ascididemin (42) [70].

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Scheme 10: Synthesis of analogues of meridine (56) [71].

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Scheme 11: Synthesis of bulky pyridoacridine as eilatin (58) [72].

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Scheme 12: Synthesis of AK37 (59), analogue of kuanoniamine A (60) [73].

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Figure 6: Biosynthesis pathway I [74].

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Figure 7: Reaction illustrating catechol and kynuramine as possible biosynthetic precursors [75].

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Figure 8: Biosynthesis pathway B deduced from the feeding experiment A using labelled precursors [76].

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Figure 9: Proposed biosynthesis pathway [47].

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Figure 10: 4H-Pyrido[2,3,4-kl]acridin-4-one as a cytotoxic pharmacophore.

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Figure 11: 7H-Pyrido[2,3,4-kl]acridine as a cytotoxic pharmacophore.

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Figure 12: 9H-Quinolino[4,3,2-de][1,10]phenanthrolin-9-one as a cytotoxic pharmacophore.

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Figure 13: 8H-Benzo[b]pyrido[4,3,2-de][1,7]phenanthrolin-8-one as a cytotoxic pharmacophore.

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Figure 14: Pyrido[4,3,2-mn]pyrrolo[3,2,1-de]acridine as a cytotoxic pharmacophore.

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Figure 15: 9H-Pyrido[4,3,2-mn]thiazolo[4,5-b]acridin-9-one and 8H-pyrido[4,3,2-mn]thiazolo[4,5-b]acridine: cyt...

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Figure 16: 9H-quinolino[4,3,2-de][1,10]phenanthrolin-9-one as an anti-mycobacterial pharmacophore.

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Figure 17: 9H-Quinolino[4,3,2-de][1,10]phenanthrolin-9-one as an antibacterial pharmacophore.

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Figure 18: Saturated and less saturated pyridine moieties as aspartyl inhibitor cores.

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Figure 19: Iminobenzoquinone and acridone cores as intercalating and TOPO inhibitor motifs found in pyridoacri...

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Review

Published 18 Sep 2015

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